Any activation of a general alarm is required to shut down the air handler supplying a means of egress. Whether it's return air stream or supply is something you'll have to check (they flip flop constantly on that one) and another issue is size of tenant space being served. It should be in the FMC which you can access for free online at floridabuilding.org
http://www2.iccsafe.org/states/Florida_Codes/index.htm
ok I looked it up for you
SECTION 606 SMOKE DETECTION SYSTEMS CONTROL
606.1 Controls required.
Air distribution systems shall be equipped with smoke detectors listed and labeled for installation in air distribution systems, as required by this section. Duct smoke detectors shall comply with UL 268A. Other smoke detectors shall comply with UL 268.
Exception: Structures classified as R-3 occupancy type.
606.2 Where required.
Smoke detectors shall be installed where indicated in Sections 606.2.1 through 606.2.3 and NFPA 90A.
Exception: Smoke detectors shall not be required where air distribution systems are incapable of spreading smoke beyond the enclosing walls, floors and ceilings of the room or space in which the smoke is generated.
606.2.1 Supply air systems.
Smoke detectors shall be installed in supply air systems with a design capacity greater than 2,000 cfm (0.9 m3/s) in the supply air duct.
Exception: Smoke detectors are not required in the supply air system where the space served by the air distribution system is protected by a system of area smoke detectors in accordance with the Florida Fire Prevention Code. The area smoke detector system shall comply with Section 606.4.
606.2.2 Common supply, return air and supply air systems.
Where multiple air-handling systems share common supply or return air ducts or plenums with a combined design capacity greater than 2,000 cfm (0.9 m3/s), the return air and supply air system shall be provided with smoke detectors in accordance with Section 606.2.1.
Exception: Reserved.
606.2.3 Return and supply risers.
Where return air and supply air risers serve two or more stories and are part of a return air and supply air system having a design capacity greater than 15,000 cfm (7.1 m3/s), smoke detectors shall be installed at each story. Such smoke detectors shall be located upstream of the connection between the return air riser and any air ducts or plenums and between the air supply source and the first branch or take-off to the areas served.